Korean Journal of Veterinary Research 2006;46(3):207-214.
Evaluation of efficacy of Mycoplasma gallisepticum 6/85 live vaccine
Hee-Jun Yoon1, Zheng-Wu Kang1, Ji-Dong Jin1, Eun-Kyung Shin1, Yong-Hoon Jeong2, Ji-Hye Jeong2, Tae-Wook Hahn1
1School of Veterinary Medicine, Kangwon National University
2Intervet Korea
닭 Mycoplasma gallisepticum 6/85 생균 백신의 효능 평가
윤희준1, 강정무1, 김길동1, 신은경1, 정용운2, 정지혜2, 한태욱1
1강원대학교 수의학부
2(주)인터베트 코리아
Mycoplasma gallisepticum (MG) continues to persist in many commercial layer farms in Korea,resulting in losses in egg production. Bacterins and live attenuated vaccines have been used for the prevention of losses caused by MG. One of these attenuated vaccines, MG 6/85 vaccine has been reported to be safe and efficacious in layers. However, MG 6/85 vaccine has not been evaluated for its safety and its efficacy in any commercial layer in Korea. Six-week-old specific pathogen-free (SPF) chickens were vaccinated with MG 6/85 vaccine by aerosol and were challenged with virulent MG R strain at 4 weeks after vaccination. The vaccinated group was able to resist challenge into the air sacs because the vaccinated group showed much less air sac lesion compared with the unvaccinated group. Each of two commercial layer farms was divided into vaccinated and unvaccinated groups. For each vaccinated gorup, MG 6/85 vaccine were sprayed at 17 week old on farm A and at 15 weeks old on farm B. Hen-day egg production, Hen-housed eggs, egg weight, mortality were evaluated until 50 week after vaccination.Compared with the unvaccinated group in each farm, the vaccinated group showed higher average egg production and egg weight, and higher hen-housed number. Results of this study are in agreement with other previous reports which demonstrated that MG 6/85 vaccine favorable effect on performance in commercial layers.
Key Words: Mycoplasma gallisepticum, 6/85 vaccine, safety, efficacy

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