| Survey of extended-spectrum β-Lactamase (ESBL) in pathogenic Escherichia coli isolated from poultry in Korea |
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Myung-Suk Sung1, Jin-Hyun Kim1, Jae-Keun Cho2, Sung-Yong Seol3, Ki-Seuk Kim1 |
1College of Veterinary Medicine, Kyungpook National University
2Health & Environmental Research Institute
3Kyungpook National University School of Medicine |
| 국내 가금유래 병원성 대장균의 extended-spectrum β-lactamase(ESBL) 특성 조사 |
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성명숙1, 김진현1, 조재근2, 설성용3, 김기석1 |
1경북대학교 수의과대학
2대구시 보건환경연구원
3경북대학교 의학전문대학원 |
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| Abstract |
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This study was conducted to investigate incidence of extended-spectrum ${eta}$-lactamase (ESBL) producing strains and characteristics of ESBL gene in pathogenic Escherichia coli isolated from poultry during the period from April 2003 to December 2005 in Korea. Among 203 isolates, 4 isolates (3 from broilers and 1 from layer) were confirmed as ESBL producing strains by double disk synergy test, polymerase chain reaction and sequencing for ${eta}$-lactamase genes. $bla_{CTX-M-15}$ and $bla_{CMY-2}$ were detected in these 4 isolates and were transferred to recipient by conjugation, respectively. Also, these ESBL producing strains were associated with multiple drug resistance. In conclusion, these results exhibit incidence of CTX-M and CMY-2 ${eta}$-lactamase in pathogenic E coli from poultry in Korea, and clinically important meaning in human. And they also suggest the needs for rapid and broad surveillance to monitor ESBL genes and R plasmid transferring resistant gene in poultry. |
| Key Words:
ESBL genes, extended-spectrum ${eta}$-Lactamase (ESBL), Korea, pathogenic Escherichia coli, poultry |
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