| Pathological description and immunohistochemical demonstration of ovine abortion associated with Toxoplasma gondii in Iran |
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Maryam Rassouli1, Golam Reza Razmi1, Ahmad Reza Movassaghi1, Mohammad Reza Bassami2, Mehrdad Sami2 |
1Department of Pathobiology, School of Veterinary Medicine, Ferdowsi University of Mashhad
2Department of Clinical Science, School of Veterinary Medicine, Ferdowsi University of Mashhad |
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| Abstract |
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The obligatory intracellular protozoan parasite Toxoplasma gondii is a major world wide cause of infectious ovine abortion. In some different diagnostic techniques that are being used to detect this pathogen in ovine fetuses, immunohistochemistry (IHC) is a very sensitive and expensive one. Histopathology is not truly a specific and sensitive test for Toxoplasma infection but it can be helpful to choose some suspected tissues for IHC. In this study 9.5% of 200 samples (aborted ovine fetuses internal organs such as brain, liver, heart, lung, kidney, spleen) (4.6~14.4% with 95% CI) were positive in IHC with a very good logical agreement among different diagnostic techniques (${kappa}=0.73$, 0.8) and with no significant difference among different fetal age groups (p > 0.05). |
| Key Words:
histopathology, immunohistochemistry, Iran, ovine abortion, Toxoplasma gondii |
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