Korean J Vet Res > Volume 53(1); 2013 > Article
Korean Journal of Veterinary Research 2013;53(1):1-5.
DOI: https://doi.org/10.14405/kjvr.2013.53.1.001    Published online March 31, 2013.
Pathological description and immunohistochemical demonstration of ovine abortion associated with Toxoplasma gondii in Iran
Maryam Rassouli1, Golam Reza Razmi1, Ahmad Reza Movassaghi1, Mohammad Reza Bassami2, Mehrdad Sami2
1Department of Pathobiology, School of Veterinary Medicine, Ferdowsi University of Mashhad
2Department of Clinical Science, School of Veterinary Medicine, Ferdowsi University of Mashhad
The obligatory intracellular protozoan parasite Toxoplasma gondii is a major world wide cause of infectious ovine abortion. In some different diagnostic techniques that are being used to detect this pathogen in ovine fetuses, immunohistochemistry (IHC) is a very sensitive and expensive one. Histopathology is not truly a specific and sensitive test for Toxoplasma infection but it can be helpful to choose some suspected tissues for IHC. In this study 9.5% of 200 samples (aborted ovine fetuses internal organs such as brain, liver, heart, lung, kidney, spleen) (4.6~14.4% with 95% CI) were positive in IHC with a very good logical agreement among different diagnostic techniques (${kappa}=0.73$, 0.8) and with no significant difference among different fetal age groups (p > 0.05).
Key Words: histopathology, immunohistochemistry, Iran, ovine abortion, Toxoplasma gondii

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