Effect of Iodine-131 Administration on the Liver of Guinea Pig

Lee, Heung Shik; Lee, Kang Wook

Korean Journal of Veterinary Research 1972;12(1):15-19.

Heung Shik Lee¹, Kang Wook Lee²

¹School of Medicine, Kyung Hee University
²College of Animal Husbandry, Konkuk University

방사성 옥소(¹³¹I)가 Guinea Pig의 간장에 미치는 영향

이흥식¹, 이강욱²

¹경희대학교 의과대학
²건국대학교 축산대학

Abstract

This experiment was carried out to investigate the effect on the liver of guinea pig after administration of 4.5mCi per Kg. body wt. with iodine-131. The histological changes in the liver were degeneration of hepatic cells, congestion of sinusoids, dilatation of bile ducts, perivascular infiltration of lymphocytes, and dissociation of hepatic cords. A marked histological changes were produced after treatment for 14 days and the morphological recoveries were observed 28 days after the treatment.