Korean Journal of Veterinary Research 2008;48(1):1-8.
Expression of galectin-3 in the testis and epididymis of mouse
Won-Jun Kim1, Hwanglyong Kim1, Hong-Gu Joo1, Taekyun Shin1, Yong-Duk Lee2, Seungjoon Kim3
1College of Veterinary Medicine, Cheju National University
2Korean Racing Authority
3College of Veterinary Medicine, Kyungpook National University
생쥐 고환 및 부고환에서 galectin-3의 발현
김원준1, 김황룡1, 주홍구1, 신태균1, 이용덕2, 김승준3
1제주대학교 수의과대학
2한국마사회 장수육성목장
3경북대학교 수의과대학
The testis and epididymis are important organs of the male reproductive system; the functionis to produce, mature, transport, and store sperm. It is important to understand the localization and expressionof specific proteins based for the studies of its physiological processes. In this study, we investigated theexpression and distribution of galectin-3, one of beta-galactoside-binding proteins, in the testis andepididymis of mouse using western blot and imunohistochemistry. Western blot analysis revealed that theexpression of galectin-3, 29 kDa protein, was low in the testis. In the epididymis, high expression wasdetected in the body and tail part, but moderate expression in the head part. By immunohistochemicalanalysis, we found that positive localization of galectin-3 was detected in some myoid cells and Leydigin the epithelium of epididymis, especially in the epithelium of both body and tail of epididymis. Collectively,these results suggest that galectin-3 is constitutively expressed in the testis and epididymis of mouse withvarying intensity, and the role of galectin-3 in the male reproductive organ may be involved in the specificfunction of its structures.
Key Words: epididymis, galectin-3, mouse, testis

Browse articles
For contributors
Editorial Office
#401-1, 85 Bldg., College of Veterinary Medicine, Seoul National University
1 Gwanak-ro, Gwanak-gu, Seoul 08826, Korea
Tel: +82-2-880-1229    Fax: +82-2-878-9762    E-mail: jvs@ksvs.or.kr                

Copyright © 2024 by The Korean Society of Veterinary Science.

Developed in M2PI

Close layer
prev next